Arntl Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comArntl Polyclonal Antibody for Rat(Rattus norvegicus)

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Arntl (Gene name),

Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Protein name ), BMAL1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Arntl(Bmal1;Tic);

Protein name:

Aryl hydrocarbon receptor nuclear translocator-like protein 1;

Alternative:

Tic;Brain and muscle ARNT-like 1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Component of the circadian clock oscillator which includes the CRY proteins, CLOCK or NPAS2, ARNTL or ARNTL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Efficient DNA binding requires dimerization with another bHLH protein. Heterodimerization with CLOCK is required for E-box-dependent transactivation, for CLOCK nuclear translocation and degradation, and, for phosphorylation of both CLOCK and ARNTL. Interaction with PER and CRY proteins requires translocation to the nucleus. Interaction of the CLOCK-ARNTL heterodimer with PER or CRY inhibits transcription activation. Interacts with HSP90. Part of a nuclear complex which also includes GNB2L1/RACK1 and PRKCA; GNB2L1 and PRKCA are recruited to the complex in a circadian manner.

Function:

ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

626

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

626:

AVIMSLLEAD | AGLGGPVDFS | DLPWPL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9EPW1

UniGene:

Rn.14532

KEGG:

rno:29657

Pfam:

PF00010

Uniprot:

Q9EPW1

FOR

ELISA Kit for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

E10272h

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Manual:

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Packing:

96T

Range:

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ELISA Kit for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

E10272c

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Packing:

96T

ELISA Kit for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

E10272r

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Packing:

96T

ELISA Kit for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

E10272m

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Packing:

96T

CLIA Kit for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

U10272h

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MSDS:

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Packing:

96T

CLIA Kit for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

U10272c

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

U10272m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

U10272r

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MSDS:

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96T

Polyclonal Antibody for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

P10272Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

P10272Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Cat.:

P10272Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

Protein for Rat Aryl hydrocarbon receptor nuclear translocator-like protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Circadian oscillation of BMAL1, a partner of a mammalian clock gene clock, in rat suprachiasmatic nucleus."
Honma S. , Ikeda M. , Abe H. , Tanahashi Y. , Namihira M. , Honma K. , Nomura M.
Biochem. Biophys. Res. Commun.250:83-87(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain.
2.

"Cloning and chromosomal localization of a new member of the bHLH/PAS transcription factor family."
Wolting C.D. , McGlade C.J.
Mamm. Genome9:463-468(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Brain.
3.

"Sequence of Rat BMAL1g' cDNA."
Jac M. , Sladek M. , Sauman I.
Submitted (2001-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
strain: Wistar.
tissue: Brain.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Prostate.
5.

"Thyroid transcription factor 1, a homeodomain containing transcription factor, contributes to regulating periodic oscillations in GnRH gene expression."
Matagne V. , Kim J.G. , Ryu B.J. , Hur M.K. , Kim M.S. , Kim K. , Park B.S. , Damante G. , Smiley G. , Lee B.J. , Ojeda S.R.
J. Neuroendocrinol.24:916-929(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
6.

"Downregulation of core clock gene Bmal1 attenuates expression of progesterone and prostaglandin biosynthesis-related genes in rat luteinizing granulosa cells."
Chen H. , Zhao L. , Kumazawa M. , Yamauchi N. , Shigeyoshi Y. , Hashimoto S. , Hattori M.A.
Am. J. Physiol.304:C1131-C1140(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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